Our Clinician Scientist Profile: Holger Schneider

Picture of von Holger Schneider Clinician Scientist of the CRCTRR 205

 

Dr. med. Holger Schneider

Universitätskrankenhaus
Klinikum der Universität München


State examination: 
2012, München

Promotion:  Gq/11-gekoppelte Rezeptoren in der lokalen Vasoregulation, 2013, München (Pharmakologie und Toxikologie)

Research theme: Arterielles Remodelling bei primärem Hyperaldosteronismus

CRCTRR 205 Projects:  B12, B14, B15, B17, S02

 

Publications:

Pogoda K, Mannell H, Blodow S, Schneider H, Schubert KM, Qiu J, Schmidt A, Imhof A, Beck H, Tanase LI, Pfeifer A, Pohl U, Kameritsch P: NO Augments Endothelial Reactivity by Reducing Myoendothelial Calcium Signal Spreading: A Novel Role for Cx37 (Connexin 37) and SHP-2. Arterioscler Thromb Vasc Biol. 2017 Dec; 37(12):2280-2290; Impact factor 6,6

Schubert KM, Qiu J, Blodow S, Wiedenmann M, Lubomirov LT, Pfitzer G, Pohl U, Schneider H: The AMP-Related Kinase (AMPK) Induces Ca2+-Independent Dilation of Resistance Arteries by Interfering With Actin Filament Formation. Circ Res. 2017 Jul 7;121(2):149-161; Impact factor 14,0

Kirsch J, Schneider H, Pagel JI, Rehberg M, Singer M, Hellfritsch J, Chillo O, Schubert KM, Qiu J, Pogoda K, Kameritsch P, Uhl B, Pircher J, Deindl E, Müller S, Kirchner T, Pohl U, Conrad M, Beck H: Endothelial Dysfunction, and A Prothrombotic, Proinflammatory Phenotype Is Caused by Loss of Mitochondrial Thioredoxin Reductase in Endothelium. Arteriosclerosis, Thrombosis and Vascular Biology; 2016 Sep;36(9):1891-9;
Impact factor 6,0

Fey T, Schubert KM, Schneider H, Fein E, Kleinert E, Pohl U, Dendorfer A:
Impaired endothelial shear stress induces podosome assembly via VEGF up-regulation;
FASEB J. 2016 Aug;30(8): 2755-66; Impact factor 5,0

Schneider H, Schubert KM, Blodow S, Kreutz C-P, Erdogmus S, Wiedenmann M, Qiu J,
Fey T, Ruth P, Lubomirov LT, Pfitzer G, Mederos y Schnitzler M, Hardie DG, Gudermann T, Pohl U: AMPK dilates resistance arteries via activation of SERCA and BKCa channels in smooth muscle; Hypertension. 2015 Jul;66(1):108-16; Impact factor 7,6

Blodow S*, Schneider H*, Storch U*, Wizemann R, Forst AL, Gudermann T, Mederos y Schnitzler M: Novel role of mechanosensitive AT1B receptors in myogenic vasoconstriction; Pflugers Arch. 2014 Jul;466(7):1343-53; *shared first authorship; Impact factor 4,9

 

Awards:

2018: Deutsche Gesellschaft für Endokrinologie: Travel award
2016: Georg-Heberer-Award der Chiles Foundation, Portland, Oregon (€ 12.500)
2014: 11th International Symposium on Resistance Arteries (ISRA) Banff, Kanada: Travel award